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6th International Congress on Infectious Diseases

London, UK

Siripan Sangmala

Prince of Songkla University, Thailand

Title: Risk factors and outcomes of extended-spectrum β-lactamase-producing Enterobacteriaceae urinary tract infection among patients with long-term urinary catheterization

Biography

Biography: Siripan Sangmala

Abstract

Catheter-associated urinary tract infection (CA-UTI) is an important nosocomial infection that cause a bad clinical outcome. Prolong catheterization is one of the risk factors of CAUTI. Extended-spectrum β-lactamase-producing (ESBL) Enterobacteriaceae emerges worldwide as one of the important pathogenic organisms for nosocomial infection and cause poor clinical outcomes. We conducted retrospective cohort study among the patients with long-term urinary catheterization at Songklanagarind Hospital, a tertiary-care hospital in Southern Thailand from January 2010 to December 2014, focusing on the clinical outcomes, economic burden and risk factors of those with ESBL Enterobacteriaceae CA-UTI. We defined prolong catheterization for more than 15 days. We found 9726 patients with urinary catheterization, 4176 patients were categorized as the patients with long-term urinary catheterization. Th e patients with ESBL CA-UTI had more hazardous outcomes including mortality, hospital costs, and the length of stay than those infected with non-ESBL CA UTI. Retention of other medical devices, immunocompromised status, emergent indication for admission, initial admission to intensive care units, invasive procedures/operations, previous use of antibiotics (aminoglycoside, fluoroquinolone, broad-spectrum cephalosporin, carbapenem, beta lactamase inhibitor antibiotic) is the significant risk factor for CAUTI in long-term catheterization.